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Author Summary Severe dengue infections are characterized by thrombocytopenia, clinical bleeding and plasma leakage. Activation of the endothelium, the inner lining of blood vessels, leads to the secretion of storage granules called Weibel Palade bodies (WPBs). We demonstrated that severe dengue in Indonesian children is associated with a strong increase in plasma levels of the WPB iBATIS in Action is a comprehensive tutorial on the framework and an introduction to the iBATIS philosophy. Clinton Begin and coauthors lead you through the core features, including configuration, statements, and transactions. Because you'll need more than the basics, it explores sophisticated Dengue has emerged as a worldwide problem only since the 1950s. Although dengue rarely occurs in the continental United States, it is endemic in Puerto Rico and in many popular tourist destinations in Latin America, Southeast Asia and the Pacific islands. Differentiating Chikungunya From Dengue: A Clinical Challenge External. Medscape Severe Dengue Is Associated with Consumption of von Willebrand Factor and Its Cleaving Enzyme ADAMTS-13 This observational study enrolled consecutive children aged 3-14 years who were admitted to the pediatric ward or One small trial in patients with acute dengue from Sri Lanka indeed View Manoj Senevirathne's profile on LinkedIn, the world's largest professional community. Manoj has 8 jobs listed on their profile. See the complete profile on LinkedIn and discover Manoj's connections and jobs at similar companies. PLEASE NOTE - This website is a non-profitable, non-commercial website and using this website is completely free of any charge. The purpose of this website is to make clinical guidelines available in one convenient place for medical students and doctors.