What is Graft Versus Host Disease Market?

The recommended first-line treatment for both acute and chronic GvHD is systemic steroid therapy (methylprednisolone and prednisone) as a monotherapy and in combinations as well. However, around half of those patients receiving the treatment in first line become refractory to steroid therapy by Graft Versus Host Disease Market.

At present, there are no exact consensus around the management of steroid refractory pool. Ruxolitinib (Jakafi) and Ibrutinib (Imbruvica) are the only two United States Food and Drug Administration (USFDA) approved therapies for the treatment of steroid refractory acute and chronic GvHD, respectively.

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