Isabelles Luxuriance Clinical tests shows that taking Jouvence gives numerous health benefits and shows up most notably in the patient's hair, skin, and nails. Other very effective natural ingredients include essential oils such as grapeseed oil, macadamia oil and avocado oil. For most people, the 'sunset years' are the best time of their lives. At the same time, improve micro-circulation to your face which stimulates production of collagen, improve tone and texture, and improve or eliminate wrinkles.