Or, you may take two single doses three days apart to manage severe symptoms. Over-the-counter treatment. Over-the-counter antifungal vaginal suppositories and creams are effective for many women, and these are a safe choice V-Tight Gel Reviews during pregnancy. Treatment usually lasts from three to seven days V-Tight Gel. Make a follow-up appointment with your doctor if symptoms don't resolve after treatment, or if they return within two months of treatment.