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al muscle cells. All three mechanisms can increase the activation of 'satellite' cells (muscle precursor cells) as well as activation of the important mTOR pathway. As you can see, Practical applications Many coaches argue that a progressive overload via low repetitions based on basic barbell lifting is enough to build maximal hypertrophy. The reason why this advice is so effective is that many individuals do not really acquire the importance of gaining strength in their relationship to muscle growth. However, alone is not enough for maximum profits. As Brad and I detailed in our previous article, there are many neural (non-hypertrophic) mechanisms through which a

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