According to a post by WebMD, pumpkin seed oil extract may help with BPH symptoms and may help shrink the prostate size. It may also be helpful when used with other supplements such as saw palmetto.Prostate enlargement is an age-related condition affecting around 70% of men between 50 and 90. The condition develops due to fibrosis and weakening of the muscle tissue in the prostate, which impairs the gland’s functionality. Repeated contraction and dilation of muscle fibers, causing them to break.