yet POPs might help explain why weight loss doesn’t improve everyone’s health equally — in some people, the increased toxic load from POPs offsets the benefits of carrying around less fat. Medically, you need detoxification when you poison yourself with drugs, such as alcohol. Such programs can claim to cleanse your whole body or specific organs.

It can be depleted by large amounts of toxins and/or drugs passing through the liver, as well as starvation or fasting. Phase II reactions may follow Phase I for some molecules or act directly on the toxin or metabolite. For efficient phase two detoxification, the liver cells require sulphur-containing amino acids such as taurine and cysteine.

As for overindulgence of alcohol or food, less is always best when it comes to liver health, and cleanses have not been proven to rid your body of damage from excess consumption. According to the Mayo Clinic, the "toxins" typically remain unspecified and there is little to no evidence of toxic accumulation in patients treated.

Make sure you also eat regularly as skipping meals or going long periods without eating can encourage bloating. Learn to manage your stress as this can affect movement and contraction of the GI tract and is also considered to be a risk factor for Irritable Bowel Syndrome. New and evolving research has also begun suggesting that the diversity of bacteria in your gut may even influence mental health and play a role in obesity by way of the gut-brain axis.

But as they experience withdrawal symptoms, a short-term medication plan for this detox stage might have them take certain medications for a limited period of time to ease discomfort. A “cold turkey” detox means stopping use of all drugs and substances with nothing more than medical supervision to aid you in case of an emergency. There’s no pharmacological assistance, and patients experience the full brunt of the withdrawal symptoms for as long they last. For some drugs, these can be quite intense and last for a couple of weeks or longer.

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